Eruptive Seborrhoeic Keratoses Induced by Oral Esomeprazole: A Coincidental Finding or Linked Pathogenesis?

Aim: Eruptive seborrhoeic keratoses are characterized by rapid onset of multiple seborrhoeic keratoses. They can be associated with internal malignancies, inflammatory dermatoses and drug reactions. Our aim was to present a case with eruptive seborrhoeic keratoses appeared during treatment with oral esomaprazole and to discuss possible etiopathogenesis.

Presentation of Case: Herein we report a 24-year-old female patient with eruptive seborrhoeic keratoses appeared during 1-year treatment with oral esomeprazole.

Discussion and Conclusion: Although, the association between esomeprazole treatment and eruptive seborrhoeic keratoses may be a coincidence, previously reported growth factor changes in both conditions may be pointing out a linked pathogenesis.