UNUSUAL HORMONAL OVERLAP SYNDROME: VAN WYK-GRUMBACH SYNDROME

Hypothyroidism commonly results in a delayed sexual development in most of the affected children. The rare association of Isosexual Precocious Puberty with delayed bone age in children with longstanding untreated hypothyroidism is called Van Wyk-Grumbach syndrome (VWGS). Most cases of the syndrome have been reported in girls, including its first ever description by Van Wyk and Grumbach. We describe a case of an adolescent boy who presented with the above syndrome and its classical features.