SAYINER, HAKAN SEZGIN and KANDEMIRLI, FATMA (2016) THE REACTION MECHANISM STUDY OF CEFTRIAXONE AND PHENYLALANINE. Journal of International Research in Medical and Pharmaceutical Sciences, 9 (2). pp. 83-90.
Full text not available from this repository.Abstract
Interaction between ceftriaxone used in the most commonly antibiotics combination in Staphylococcal scalded skin (SSS) infections and phenylalanine that is one of carrier-mediated transport system in the blood-brain barrier. It was investigated whether interaction between phenyl alanine and ceftriaxone occur and this study was performed by using semi-empirical- Parameterization Method 6 (PM6). Quantum chemical calculations were used to analyze the formation of a peptide bond between phenylalanine and Ceftriaxone molecules. Both concerted and a stepwise and mechanism were considered. The energetic requirements for the stepwise and concerted were determined.
| Item Type: | Article |
|---|---|
| Subjects: | STM Open Academic > Medical Science |
| Depositing User: | Unnamed user with email admin@eprint.stmopenacademic.com |
| Date Deposited: | 16 Jan 2024 05:11 |
| Last Modified: | 16 Jan 2024 05:11 |
| URI: | http://publish.sub7journal.com/id/eprint/1738 |
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