Karai, Oumaima and Aouine, Younas and Alami, Anouar and Faraj, Hassane and Hallaoui, Abdelilah El (2020) Characterization and Antibacterial Activity of New α- Aminoester Derivative, Synthesized via N-Alkyaltion of Methyl α-Azido Glycinate. In: Theory and Applications of Chemistry Vol. 4. B P International, pp. 93-99. ISBN Theory and Applications of Chemistry Vol. 4
Full text not available from this repository.Abstract
The amino ester derivative was synthesized via N-alkylation of methyl -azido glycinate Nbenzoylated
1 with methyl 2-amino-2-phenylacetate in methylene chloride and in presence of
triethylamine as basic catalyst. The structure of the prepared compound was determined by
spectroscopic methods: 1H-NMR, 13C-NMR, MS data, elemental analysis and confirmed by X-Ray
diffraction. This compound was screened in vitro for its antibacterial activity against Gram-positive
bacteria (Bacillus subtilis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli,
Pseudomonas aeruginosa and Salmonella enteric). The synthesized compound showed an
interesting inhibitory effect against all the strains tested.
| Item Type: | Book Section |
|---|---|
| Subjects: | STM Open Academic > Chemical Science |
| Depositing User: | Unnamed user with email admin@eprint.stmopenacademic.com |
| Date Deposited: | 24 Nov 2023 05:06 |
| Last Modified: | 24 Nov 2023 05:06 |
| URI: | http://publish.sub7journal.com/id/eprint/1715 |
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