THE EFFECT OF ARTEETHER TO PLASMODIUM PINOTTII

The effect of arteether, an antimalarial drug was studied on Plasmodium pinottii (pigeon malarial parasite) inoculated to one week and ten week old chicks. Significant difference in parasitemia was observed between control and treated chicks. In one week old control chicks the parasites were at peek level on 10th day but in treated parasites disappeared on 14th day. In ten week old control chicks the parasites were at peak level on 9thday but in case of treated, the parasites disappeared on 14th day. Prophylactic effect of arteether was also studied on P. pinottii inoculated to one and ten week old chicks. In one week old control chicks, the parasites were at peak level on 10th day but in experimental chicks parasites were completely disappeared on 11th day. In case of ten week old control chicks parasites were at peak level on 9th day but in experimental chicks parasites disappeared on 18th day.