Role of Ascorbic Acid in Fresh Myocardial Infarction–As a Diagnostic Marker

This chapter was planned to evaluate the status of ascorbic acid in patients suffering from MI and to compare them with normal healthy individuals. Magnesium is an essential micronutrient for people and is crucial in maintaining healthy cardiac function. It functions as a cofactor in a number of the body's enzyme systems, and myocardial cells are one of its target tissues. The upkeep of the myocardium's normal functional integrity depends on a lot of things including magnesium ions. Decreased serum magnesium and ascorbic acid have been associated with an increased risk of myocardial infarction (MI). he present study was undertaken in the Department of Biochemistry and the Department of Medicine, Guru Nanak Dev Hospital, attached to Government Medical College, Amritsar. Fifty patients in the age group 30–90 years who had attended the emergency Wards of Guru Nanak Dev Hospital, Amritsar were selected for the study. The study was planned to evaluate the status of ascorbic acid in patients suffering from MI and to compare them with normal healthy individuals. Plasma ascorbic acid levels and lipid profiles were also estimated. In our study, we observed that the difference between the plasma ascorbic acid levels of normal individuals and the patient of MI was statistically highly significant (p<0.001). It was observed that plasma ascorbic acid levels were low as age advanced. High risk for MI reveals that men, the elderly, smokers, diabetics, and hypertensives have lowered plasma ascorbic acid levels. It was also seen that the maximum number of subjects was found the age of 51–70 years in MI patients. This study will conclude that Ascorbic acid is an important diagnostic marker in the case of fresh MI. Plasma ascorbic acid may be done as a routine investigation for the assessment of MI and its complications.